Fatemeh Abedini

Molecular Genetics Researcher & Biotechnology Specialist

Tehran, IR.

About

Highly accomplished Molecular Genetics PhD student with a strong background in advanced laboratory techniques, genetic analysis, and scientific research. Proven expertise in diverse methodologies including NGS, Mass Spectrometry, PCR, and cell culture, complemented by a robust publication record in esteemed journals. Eager to leverage extensive research experience and analytical skills to drive innovation and contribute to cutting-edge advancements in biotechnology and diagnostics.

Work

Nilou Laboratory

|

NGS Specialist

Tehran, Tehran, Iran (Islamic Republic of)

→

Summary

Specialized in Next-Generation Sequencing (NGS) applications, primarily focusing on Non-Invasive Prenatal Testing (NIPT) within a clinical diagnostics laboratory.

Highlights

Performed Non-Invasive Prenatal Testing (NIPT) using advanced NGS techniques, accurately detecting chromosomal abnormalities in fetal DNA for over 100 cases.

Managed the entire NIPT workflow, from meticulous sample preparation and library construction to high-throughput sequencing and initial data quality control.

Ensured strict adherence to laboratory protocols and quality control standards, contributing to a 99% reliability rate in diagnostic results.

Contributed to the timely processing of NIPT samples, significantly reducing turnaround times and supporting critical prenatal diagnostic services.

Razi Pathobiology & Genetic Laboratory

|

Metabolic Department Specialist

Tehran, Tehran, Iran (Islamic Republic of)

→

Summary

Led advanced metabolic analysis and diagnostic testing within a genetic laboratory, applying a range of sophisticated biochemical and analytical techniques.

Highlights

Executed complex analytical procedures including HPLC, Tandem Mass Spectrometry, and GC/Mass to support metabolic disease diagnostics, ensuring high accuracy in over 500 patient samples.

Performed protein and hemoglobin electrophoresis, contributing to the identification and characterization of genetic disorders and blood abnormalities for clinical diagnosis.

Conducted ELISA assays for quantitative analysis of biomarkers, providing critical data for patient diagnosis and advancing research studies.

Managed comprehensive sample preparation and instrument calibration for various analytical platforms, maintaining operational efficiency and data integrity across diverse projects.

Education

National Institute of Genetic Engineering and Biotechnology

Tehran, Tehran, Iran (Islamic Republic of)
→
PhD Student Molecular Genetics

Courses

Advanced Molecular Biology

Genomics

Bioinformatics

Statistical Genetics

Gene Expression Analysis

Sistan and Baluchestan University

Zahedan, Sistan and Baluchestan, Iran (Islamic Republic of)
→
MSc Biology (Genetics) Grade:

Courses

Molecular Genetics

Polymorphism Analysis

Statistical Analysis

Gene Expression

Shahed University

Tehran, Tehran, Iran (Islamic Republic of)
→
BSc Cellular and Molecular Biology (Genetics) Grade:

Courses

Cell Biology

Molecular Biology

Genetics

Biochemistry

Microbiology

Publications

Serotonin Receptors and Acetylcholinesterase Gene Expression Alternations: The Potential Value on Tumor Microenvironment of Gastric Cancer.

Oncology

Co-authored research investigating the alterations of serotonin receptors and acetylcholinesterase gene expression, highlighting their potential role in the tumor microenvironment of gastric cancer.

A Novel Report of Serotonin Receptors Antagonists Inducing Apoptosis in Human Lung Carcinoma Cells.

J Cancer Res Therap Oncol

Contributed to a novel study on the efficacy of serotonin receptor antagonists in inducing apoptosis within human lung carcinoma cells, offering insights into potential therapeutic strategies.

The composition of lung microbiome in lung cancer: a systematic review and meta-analysis.

Bmc Microbiology

Co-authored a systematic review and meta-analysis examining the composition of the lung microbiome and its implications in lung cancer development and progression.

Analysis of IL-33 gene polymorphism (rs1157505 C/G, rs11792633 C/T) and risk of vesicoureteral reflux in southeast of Iran.

The Journal of Biomedicine and Health (JBH)

Conducted comprehensive analysis of IL-33 gene polymorphisms and their association with the risk of vesicoureteral reflux in the population of southeast Iran, presented at the Iranian Genetics Congress.

FACTORS INVOLVED IN TISSUE REGENERATION.

J REGEN MED

Authored a review article exploring key factors and mechanisms involved in tissue regeneration, contributing to the understanding of regenerative medicine.

Languages

Persian

English

Certificates

Scientific Paper Writing Workshop

Royan Institute

Metagenomics Data Analysis with Galaxy

Iranian Bioinformatics Society

Metagenomics Analysis

Iranian Bioinformatics Society

CRISPR Technology Training

National Institute of Genetic Engineering and Biotechnology

MS Spectrometer Training: Newborn Screening & Acylcarnitine/Organic Acids Analysis

Shimane University

Operation and Application Training for MS Spectrometer

Shimadzu Corporation

Stem Cell Culture (Isolation and culture of mouse spermatogonial stem cells)

Iranian Society of Embryology & Reproductive Biology, Mazandaran University of Medical Science

Skills

Laboratory Techniques

RNA and DNA Extraction, Spectrophotometry, DNA Gel Electrophoresis, RFLP, Tetra-arms PCR, Real-time PCR, Cell Culture, CRISPR, HPLC, Tandem Mass Spectrometry, GC/Mass, Protein and Hb Electrophoresis, ELISA, Non-Invasive Prenatal Testing (NIPT).

Data Analysis & Bioinformatics

Statistical Analysis (SPSS), Metagenomics Analysis, Oligo Primer Analysis Software, Galaxy, Polymorphism Analysis, Gene Expression Analysis.

Research & Development

Primer Design, Dissertation Research, Scientific Writing, Literature Review, Experimental Design.